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KMID : 0379119830110010067
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Korean Journal of Mycology
1983 Volume.11 No. 1 p.67 ~ p.67
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Studies on Constituents of Higher Fungi of Korea (42)
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Abstract
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The carpophores of Xeromphalina campanella and Craterellus cornucopioides which were collected at the Gwang-neung area. Gyeong-Gi Province, in 1981 were studied for their antitumor constituents. The carpophores were extracted with hot water and alcohol precipitate were obtained. These precipitates were brownish powder which were used as samples in antitumor test. The antitumor activity of each sample was tested against sarcoma 180 implanted subcutaneously in ICR mice. The sample obtained from the carpophores of X. campanella showed the inhibition ratios of 47% and 58% at the dose levels of 20㎎ and 50㎎/㎏/day, respectively. The sample obtained from the carpophores of C. cornucopioides showed no activity. The chemical analysis of the antitumor fraction of X. campanella showed that it contained a polysaccharide. The hydrolysates of the polysaccharide moiety contained five monosaccharides: glucose, galactose, mannose, fucose and xylose.
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